Title of article :
Difference in Relative Telomere Length between Sudanese and Chinese Individuals
Author/Authors :
Tamomh, Abdelhakam G Department of Microbiology and Immunology - College of Medical Laboratory - Dalian Medical University - Dalian, China , Liu, Hui Department of Microbiology and Immunology - College of Medical Laboratory - Dalian Medical University - Dalian, China
Pages :
6
From page :
1
To page :
6
Abstract :
Background: Racial variations in the relative telomere length have been clearly described or frequently studied. The relative telomere length has emerged as a biological aging marker; however, the difference in the telomere length is debatable between Sudanese and Chinese individuals. Objectives: The current study investigated the difference in the relative telomere length between Sudanese and Chinese subjects. Methods: The blood samples of Sudanese and Chinese healthy people were randomly collected, and their deoxyribonucleic acid was obtained in this study. The relative telomere length was measured by the quantitative polymerase chain reaction. The difference in the relative telomere length was analyzed using the Mann-Whitney U test. The degree of distribution in the relative telomere length was assessed by the two-sample Kolmogorov-Smirnov Z test. Results: According to the obtained results, the difference in the relative telomere length between Sudanese and Chinese individuals was statistically significant (P<0.05). The frequency of the relative telomere length distributed in Chinese subjects was statistically higher than the frequency reported for the Sudanese subjects (P<0.05). Conclusion: A great difference was observed in the relative telomere length between Sudanese and Chinese populations indicating the variation between Sudanese and Chinese races.
Keywords :
Environmental factors , Ethnic groups , Genetic factors , Relative telomere length , qPCR
Journal title :
Iranian Red Crescent Medical Journal
Serial Year :
2020
Record number :
2655703
Link To Document :
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