Author/Authors :
AMARA, AMRO A. Mubarak City for Scientific Research and Technological Applications - Genetic Engineering and Biotechnology Research Institute - Protein Research Department, Egypt , AMARA, AMRO A. King Saud University - Microbiology Division, Pharmaceutics Department, Saudi Arabia , MOAWAD, HASSAN Mubarak City for Scientific Research and Technological Applications - Genetic Engineering and Biotechnology Research Institute - Protein Research DepartmentAlexandria, Egypt , MOAWAD, HASSAN National Research Center, Egypt
Abstract :
PHAs are a group of intracellular biodegradable polymer produced by (most) bacteria under unbalanced growth conditions. A series of enzymes are involved in different PHAs synthesis, however PhaC synthases are responsible for the polymerization step. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reduces equivalents. PHAs are converted again to soluble components by another pathways and enzymes for the degradation process. PHAs depolymerases are the responsible enzymes. This review is designed to give the non-specialists a condense background about PHAs especially for researcher and students in medicinal and pharmaceutical field.
