Title of article :
Vaginal Adenosis in Two Patients with No History of Diethylstilbestrol: A Case Report
Author/Authors :
Hasanzadeh, Malihe Department of Obstetrics and Gynecology - Fellow of Gynecology Oncology - Women’s Health Research Center - Faculty of Medicine - Mashhad University of Medical Sciences - Mashhad, Iran , Nourbakhsh, Sara Medical Student - Faculty of Medicine - Mashhad University of Medical Sciences - Mashhad, Iran , Jafarian, Amir Hosein Department of Pathology - Faculty of Medicine - Mashhad University of Medical Sciences - Mashhad, Iran , Malakuti, Parnian Medical Student - Faculty of Medicine - Szeged University of Medical Sciences - Szeged - Hungary
Abstract :
Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding . About 90% of women exposed to
diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis in
female fetus. DES has been reported rarely with no history of fetal use.
Case Presentation: In this article, we report two vaginal adenosis patients with no history of DES during pregnancy. There was no vaginal cancer in the follow-up of the patients .
Conclusion: Vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.
Keywords :
Clear cell adenocarcinoma , Vaginal hemorrhage , Case report
Journal title :
Journal of Obstetrics, Gynecology and Cancer Research
