Molecular mechanisms of action of topical antiaging compounds

We are an aging community where the number of aging individuals is markedly increasing. This is associated with enormous aging-related decline of the body functions and increase in the prevalence of diseases involving the skin among other organs. The aging skin does not only shows wrinkles, uneven tone, loss of elasticity, and thinning, but also exhibits delayed healing, recurrent infections, and an elevated incidence of both benign and malignant tumors. In the last decades, the need for antiaging skin treatment, which can combat both aging signs and dysfunction, has been markedly increasing. Understanding the mechanism behind skin aging will help us understand the mechanism of action, and hence the potential benefits of the claimed antiaging products. Topical substitution with sex hormones and vitamins, different antioxidants, botanical components, sunscreens, and different lipid substitutes are all included in numerous antiaging compounds. In this review, we are reporting on the mechanisms behind effectiveness of the topical noninvasive antiaging compounds in use and also on the mechanism of action of potential topical antiaging substances under research.