Title of article :
Shikimic acid from staranise (Illicium verum Hook): Extraction, purification and determination
Author/Authors :
Ramazani ، Ali Department of Chemistry, Department of Biotechnology, Department of Agronomy, dDepartment of Animal Science - Faculty of Science, Research Institute of Modern Biological Techniques (RIMBT) - University of Zanjan , Shahkarami ، Fatemeh Department of Chemistry - Faculty of Science - University of Zanjan , Zarei ، Armin Department of Chemistry - Faculty of Science - University of Zanjan , Rezayati ، Sobhan Department of Chemistry - Faculty of Science - University of Zanjan , Rezaei ، Aram Nano Drug Delivery Research Center, Health Technology Institute - Kermanshah University of Medical Sciences , Bodaghi ، Ali Department of Chemistry - Islamic Azad University, Tuyserkan Branch , Youseftabar-Miri ، Leila Department of Organic Chemistry - Faculty of Pharmaceutical Chemistry - Islamic Azad University, Tehran Medical Sciences
Abstract :
Shikimic acid (3,4,5-trihydroxy-1-cyclohexene-1-carboxylic acid) is considered as an essential biochemical metabolite in autotrophic organisms, such as plants and some bacteria, which is used to procreate the anti-influenza drug oseltamivir. Generally speaking, there are three main methods to produce shikimic acid, which are included in the chemical synthesis and microbial fermentation as well as extraction from natural plants. This review focused on the extraction of shikimic acid from Chinese star anise as the main industrial source for shikimic acid production and presents some of the conducted studies for the extraction of shikimic acid from Chinese star anise and its purification and determination over the last decade.
Keywords :
Shikimic acid , Chinese star anise , Natural plants , Extraction , Traditional Chinese medicine
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
