Author/Authors :
Riaz, M Baqai Medical University - Baqai Institute of Diabetology and Endocrinology - aDepartment of Medicine, Pakistan , Salman, A Baqai Medical University - Baqai Institute of Diabetology and Endocrinology - aDepartment of Medicine, Pakistan , Fawwad, A Baqai Medical University - Baqai Institute of Diabetology and Endocrinology - Department of Medicine, Pakistan , Iqbal Hydrie, MZ Institute of General Practice and Community Medicine - Faculty of Medicine - Department of International Health, Pakistan , Iqbal Hydrie, MZ University of Oslo, Norway - Baqai Institute of Diabetology and Endocrinology - Faculty of Medicine, Pakistan , Yakoob Ahmadani, M Baqai Medical University - Baqai Institute of Diabetology and Endocrinology - Department of Medicine, Pakistan , Basit, A Baqai Medical University - Baqai Institute of Diabetology and Endocrinology - Department of Medicine, Pakistan , Shera, AS WHO Collaborating Centre for Diabetes, Pakistan
Abstract :
This investigation aimed at assessing trends of TSH levels and associated factors in apparently normal subjects of urban Pakistan (Karachi).Materials and Methods: The survey was conducted in 2004 in Lyari, Karachi. Using a geographical imaging system, 85, 520 households were identified, of which 532 were randomly se-lected; 867 adults aged ≥25 years consented to take part in the study. Blood samples from 324 subjects were available for analyses. Subjects with previous history of thyroid disorders were excluded. Results UConclusionU: This spectrum of TSH levels highlighted a high prevalence of increased serum TSH levels in the population studied, a trend that was associated with obesity and various lipid abnormalities. Further population based studies are needed to correlate these findings with clinical parameters of hypothyroidism.
Keywords :
Thyrotropin , Sub , clinical hypothy , roidism , Obesity
