PREPARTION OF SOME NEW COUMARIN DERIVATIVES WITH MEASURING BIOLOGICAL ACTIVITY

The present study was designed to be into stages. The first stage included preparing and dignosing four compounds of Schiff s-bases throught condensing be town 3-amino coumarin (1) with aldehyde aromatic. While, the second stage included the reaction the prepared Schiff s-bases (2a-d)with the compound 4-hydroxy coumarin and the compounds produced(3a-d). The biological effects of the prepared compounds towards some positive bacteria Gram and negative Gram studied Staphylococcus aureu, Bacillus subtilis, Bacillus cereus, Psedomonase aeruginosa,. Also towards some fungi including Aspergllus niger, penicillium italicum, fusarium oxysporum