Preparation and Characterization of Derivatives of Pyrimidines in two ways Clascical and Microwave

This study includes synthesis and characterization of new pyrimidine derivatives (R or Ar-2,3,4,6,7,8- hexahydroquinazolin-5(1H)-one), via of the reaction from cyclohexane-1,3-dione with aldehyde derivatives and guanidine hydrochlorid. Using absolute ethanol as a solvent .This mixture was refluxed for (4 – 6) hrs; While maintaining the pH at 6. The same derivatives of pyrimidine were prepared in microwave way technique. The prepared compounds were characterized by melting point , FT-IR , UV- Vis 1H-NMR and 13CNMR spectroscopy .