INFLUENCES OF BACTERIA ON ECZEMA : BACTERIAL AND IMMUNE ASPECTS

This study aimed to investigate the most common aerobic bacteria associated with Eczema , preparation of bacterial crude antigen from the predominant bacterial isolate as well as determination of total IgE and IgE specific for bacterial antigen using ELISA test. Fifty (50) out of ( 80 ) eczematic patients were showing positive skin swab culture with dominance of S. aureus (58%) from both adults and children , Corynebacterium , diphtheroid species took the second rank of isolation (22% ) followed by S.epidermedis (16%) and Micrococcus species ( 10%). Patients with positive swab cultures from both sexes and two age groups showed more IgE specific for S. aureus crude antigen (65.5% )than that of S. aureus standard strain . More esosinophil absolute counts were found among patients than control group . We can conclude that bacterial infections associated with eczema makes it more severe via induction of certain mediators ( IgE ) in this study and probably through other mediators . S. took the first rank of isolation .