SYNTHESIS, CHARACTERIZATION AND KINETIC STUDIES OF SOME OXAZEPINE AND OXAZEPANE FROM REACTION OF ETHYLIMINO AND DIETHYLIMINO WITH MALEIC, SUCCINIC AND PHTHALIC ANHYDRIDE

Ethylimino and Di Ethylimino were prepared by condensation of Ethylene diamine with one equivalent and tow equivalent of substituted benzaldehyde. These ethylimino were reacted with one equivalent of maleic , succinic and phthalic anhydride in absolute ethanol to give 7- memberedheterocyclic ring system of 3-(2-amino-ethyl)-2-(2-hydroxy-phenyl)-[1,3] oxazepine and 3- (2-amino-ethyl)-2-(2-hydroxy-phenyl)-[1,3] oxazepane. Diethylimino were reacted with tow equivalent of maleic and succinic anhydride in same condition to give 2(7-membered) heterocyclic ring system of 2-(2-hydroxy-phenyl)-3-{2-[2-(2-hydroxy-phenyl) -4,7-dioxo -[1,3] oxazepine-3-yl]- ethyl}-2,3- dihydro-[1,3]oxazepine-4,7-dione and 2-(2-hydroxy-phenyl)-3-{2-[2-(2- hydroxy-phenyl) -4,7 -dioxo - [1,3] oxazepane-3-yl]-ethyl}-2,3-dihydro- [1,3]oxazepane-4,7-dione. Kinetic Studies of reaction of Ethylimino and DiEthylimino with maleic , Succinic and phthalic anhydride proved to A firstclassequation was applied to the reaction