Author/Authors :
Esmaeelzadeh Dizaji, Reza Department of Poultry Diseases - Faculty of Veterinary Medicine - University of Tehran, Tehran, Iran , Ghalyanchi Langeroudi, Arash Department of Microbiology and Immunology - Faculty of Veterinary Medicine - University of Tehran, Tehran, Iran , Vasfi Marandi, Medi Department of Poultry Diseases - Faculty of Veterinary Medicine - University of Tehran, Tehran, Iran , Hosseini, Hossein Department of Clinical Sciences - Faculty of Veterinary Medicine - Karaj Branch - Islamic Azad University, Karaj, Iran , Karimi, Vahid Department of Poultry Diseases - Faculty of Veterinary Medicine - University of Tehran, Tehran, Iran , Molouki, Aidin Department of Poultry Diseases - RAZI Vaccine and Serum Research Institute - Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran , Fallah Mehrabadi, Mohammad hossein Department of Poultry Diseases - RAZI Vaccine and Serum Research Institute - Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran
Abstract :
Background and Aims: Newcastle disease (ND) is one of the contagious viral diseases in avian species. Recently, several ND outbreaks in pigeon caused by pigeon paramyxovirus serotype-1 (PPMV-1) have been reported din limited numbers from Iran and phylogenetic studies have been conducted on partial sequence of NDV fusion (F) gene.
Materials and Methods: In the present study, ten PPMV-1, named Pigeon_paramyxovirus1_isolate_pigeon/Iran/UT_EGV1-10/2018, isolated from infected pigeons, and were subjected to partial sequencing. All isolates showed MDT of 74-80 hours, thus categorizing them as mesogenic.
Results and Conclusion: The phylogenetic analysis based on the F gene sequence revealed the isolates belong to XXI.1.1 subgenotype. According to BLAST results, the partial genome of UT-EGV1-10 had high homology with some Russian and Egyptian strains (the highest was 96.55%). The information obtained from this study can be useful in preventive measures for ND caused by PPMV-1 in pigeons.
Keywords :
Pigeon paramyxovirus serotype-1 (PPMV-1) , Partial sequencing , Fusion gene , Phylogenetic Study , Epidemiology , Iran
