Complications of Levonorgesterol Intrauterine System versus Multiload CU 375 as Contraceptive Method

Objective: To compare the complications of levonorgesterol releasing intrauterine system with multiload as a contraceptive method in women of reproductive age. Study Design: Randomized Control trial Place and Duration of Study: Department of obstetrics and gynecology , Shifa Hospital, from January 2008 to June 2009. Patients and Methods: 200 female patients of reproductive age group were included in this study selected by consecutive sampling and divided randomly (lottery method) in two groups (100 each). Informed written consent was obtained. A structural proforma was used to collect information regarding age of patients , type of intrauterine device used, continuation of use. Women were followed up to 1 year for complications. Outcome data included side effects (daysmenorrhoea , menorrhagia, vaginal discharge , intermenstrual bleeding episodes) and satisfaction rate. Results: 30% patients experienced dysmenorrhoea in Group A (Multiload) as compared to 5% patients in Mirena (Group B). Menorrhagia was observed in 40% of the females using multiload (Group A) . Intermenstrual bleeding was observed in 2% of the females (multiload group) and 10% of females (Mirena group) in first 6 months of insertion. Pelvic inflamatory disease was observed in 3% of females using multiload which lead to discontinuation of it while none was observed in mirena group. 94% of the women were satisfied in multiload (Group A) while 100% satisfaction was observed in Mirena Group (Group B). Pregnancy was not observed in both groups during study period. Conclusion: The levonorgesterol-releasing intrauterine system (LNG IUS) is a good choice for contraception.