Histopathological Spectrum of Malignant Jaw Tumors Diagnosed at Armed Forces Institute of Pathology

Objective: Histopathological analysis of malignant jaw tumours Study Design: Place and Duration of the Study: The study was carried out in the Histopathology department of A.F.I.P Rawalpindi. Materials and Methods: A total of 240 patients with malignant jaw tumours diagnosed during Jan 2006 to Dec 2010 were retrieved from AFIP tumour registry. Data regarding age, site, sex and Histopathological diagnosis was retrieved from the request forms. The slides were retrieved and the morphological features were studied. The data analysis was performed using SPSS version 16. Results:A total of 240 cases were included, 146 were male and 94 were female patients. Male pre-dominance was seen with male to female ratio 1.5 to 1. The age range varied from 3 to 90 years. Mandible was involved in 132 cases (55%) followed by 108 cases in maxilla (45%). The commonest malignant tumour involving the jaw was Squamous cell carcinoma with 168 cases followed by 30 cases of malignant salivary gland tumours. Conclusion: According to this study it is concluded that Squamous cell carcinoma is the most common malignant jaw tumour followed by malignant salivary gland tumours. The age range is wide and a male pre-dominance is observed. Mandible is the most commonly affected site.