Author/Authors :
Ahmed, Mohammed King Faisal Specialist Hospital Research Centre - Department of Medicine, Saudi Arabia , Faraz, Haroon A Wayne State University - Detroit Medical Center, USA , Almahfouz, Abdulraof King Faisal Specialist Hospital Research Centre - Department of Medicine, Saudi Arabia , Alarifi, Abdullah King Faisal Specialist Hospital Research Centre - Department of Medicine, Saudi Arabia , Raef, Hussein King Faisal Specialist Hospital Research Centre - Department of Medicine, Saudi Arabia , Al-Dayel, Fouad King Faisal Specialist Hospital Research Centre - Pathology and Laboratory Medicine, Riyadh , Al-Sugair, Abdulaziz King Faisal Specialist Hospital Research Centre - Radiology, Saudi Arabia , Alzahrani, Ali King Faisal Specialist Hospital Research Centre - Department of Medicine, Saudi Arabia
Abstract :
at present, the diagnosis of a “brown tumor”is a clinical curios-ity. It is considered to be a complication of severe and rap-idly progressive hyperparathyroidism (Hpt). Indeed, such a presentation is typical of a patient harboring a parathyroid carcinoma.The incidence of brown tumors is 3% in the benign form of primary hyperparathryoidism.1 In secondary Hpt, the incidence of brown tu-mors is under 2% and is caused by chronic renal failure.1 Brown tumors are locally destructive lesions consisting of fluid-filled cysts that are rich in highly vascularized fibrous tissue containing hemorrhagic spots.Blood pigment (hemosiderin) will accumulate, which imparts a red-dish-brown hue and hence the name “brown tumor”.1 Brown tumors are demonstrated radiologically as lesions of osteitis fibrosa cystica.1 We describe a young lady who was erroneously diagnosed elsewhere as a case of metastatic bone disease. our evaluation documented this as a case of vitamin D deficiency (VDD) causing secondary hyper-parathyroidism (sHpt) with diffuse distribution of brown tumors in her skeleton. Following vitamin D and calcium treatment, the patient improved.
