Author/Authors :
FOROUTAN, H. R. shiraz university of medical sciences - School of Medicine - Department of Pediatric Surgery, شيراز, ايران , DASMEH, U. shiraz university of medical sciences - School of Medicine - Department of Pediatric Surgery, شيراز, ايران , GERAMIZADEH, B. shiraz university of medical sciences - School of Medicine - Department of Pathology, شيراز, ايران , KAMALIPOUR, H. R. shiraz university of medical sciences - School of Medicine - Department of Anesthesiology, شيراز, ايران , TANIDEH, N. shiraz university of medical sciences - School of Medicine - Department of Pharmacology, شيراز, ايران
Abstract :
Background: One of the most important post-operation problems encountered with Hepaticojejunostomy (Kasai operation) in patients with biliary atresia is cholangitis. The aim of this study was to evaluate the efficiency of anti-reflux valve in decreasing the incidence of cholangitis after hepaticojejunostomy. Methods: Ten dogs were randomly divided into two groups of equal size. In group A Roux-en-Y cholecystojejunostomy was performer and in group B antireflux valve was also added. Three months later, liver biopsy was taken to evaluate histopatholic changes. Results: The incidence of cholangitis was significantly reduced in dogs in which anti-reflux valve procedure was performed. Conclusions: Anti-reflux valve procedure effectively decreased post-Roux-en-Y cholecystojejunostomy cholangitis in dogs. Therefore it is plausible and might be beneficial for patients being treated for biliary atresia
