Author/Authors :
Resim, Sefa Kahramanmaraş Sütçü İmam University - Faculty of Medicine - Department of Urology, Turkey , Kadıoğlu, Ateş Istanbul University - Faculty of Medicine - Department of Urology, Turkey , Akman, Tolga Istanbul University - Faculty of Medicine - Department of Internal Diseases, Turkey , Bayrak, Ayşe Gül Istanbul University - Faculty of Medicine - Department of Internal Diseases, Turkey , Efe, Erkan Kahramanmaraş Sütçü İmam University - Faculty of Medicine - Department of Urology, Turkey
Abstract :
Background: Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. Case Report: We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions. Conclusion: Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.
