Title of article :
Pityriasis Rosea Associated with Pegylated Interferon Alfa and Ribavirin Treatment in a Patient with Chronic Hepatitis C
Author/Authors :
Güner, Rahmet Yıldırım Beyazıt University - Faculty of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey , Keske, Şiran Polatlı Duatepe State Hospital - Department of Infectious Diseases and Clinical Microbiology, Turkey , Hasanoğlu, İmran Atatürk Education and Research Hospital - Department of Infectious Diseases and Clinical Microbiology, Turkey , Taşyaran, Mehmet Yıldırım Beyazıt University - Faculty of Medicine - Department of Infectious Diseases and Clinical Microbiology, Turkey
Abstract :
Background: Pityriasis rosea is an acute inflamatory skin disease that the etiology is unknown but some viral agents like human herpes virus-6 and 7 and drugs are suspected. Case report: A-58-year-old man with chronic hepatitis C was being followed up in our hospital. Pegylated interferon (PEG-IFN) alfa-2b (100 μg per week) and ribavirin (1000 mg/day) was started. In the third month of this treatment, the patient was diagnosed with pityriasis rosea (PR), which was confirmed by skin biopsy. PEG-IFN alfa-2b treatment for chronic hepatitis C was maintained and no therapy was given for PR. The lesions spontaneously improved within 5 weeks. Conclusion: Interferon and ribavirin have several cutaneous side effects. Our case is the first case of PR, emerged in a patient with chronic hepatitis C while receiving PEG-IFN alfa 2b and ribavirin.
Keywords :
Pityriasis rosea , chronic hepatitis C , ribavirin , pegylated interferon alfa , 2b
Journal title :
Balkan Medical Journal
Journal title :
Balkan Medical Journal
