Pediatric End-Stage Renal Disease: Single Center Analysis

Data describing end stage renal disease in Jordan is very limited, due to the absence of internal center as well as national registry systems. In this retrospective analysis, we define the etiology, prevalence, incidence as well as other demographic features of pediatric end stage renal disease and renal replacement therapy at King Hussein Medical Center. All children who entered the chronic dialysis program in our center from January 2001 to December 2005 were included in the study. Children who were transplanted pre-emptively were also included. A total number of 42 patients were included. The mean age at time of dialysis initiation was 11.10 ± 2.25 years; 19 (45.2%) were males. The prevalence of ESRD in Jordan children was calculated to be 14.5 patients per million. Hemodialysis (HD) was the primary modality of therapy in 40 (95.2%) patients. The most common cause of ESRD in our children was acquired glomerulopathy in 13 (31%) patients, followed by oxalosis in seven (16.7%), and neurogenic bladder in six (14.3 %). Thirteen patients were transplanted; the one and three year graft survival rates were 87.5% and 72.5%, respectively. We conclude that there are some peculiar features for pediatric ESRD in Jordan including the high incidence of oxalosis and neurogenic bladder. A national registry for children with ESRD should be established as this may have serious implications on the choice of renal replacement therapy.