Effect of Colocynthis (Citrillus colocynthis) plant extract on leukemic cells

The present research concentrated on evaluating the biological activity of Colocynthis (Citrillus colocynthis) plant oil extract on peripheral blood cells from leukemia patients using some cytogenetic parameters. when it is added to this cell in culture media in different concentration and incubated for 72 hours at 37C, the results pointed out that cell exposed to the Citrillus extract in culture media have mitotic index near to normal ranges, and number of chromosomal aberrations in cells exposed to the Citrillus extract is less than in the leukemic cells. This study considered as an attempt in survey for anti-tumor agents in medicinal plants.