Study the biological activities of Tribulus terrestris extracts

In this study the extracts of the Iraqi herb Tribulus terrestris (Al-Hassage or Al- Kutub) was done by using of polar and non polar solvents, then the biological activity of these extractants was studied in two field. First, the antibacterial activity in vitro on gram positive bacteria (Staphylococcus aureus), and gram negative bacteria (E. coli, Proteus vulgaris, Pseudomonas aerugiuosa, and Klebsiella pneumonia), all extracts showed considerable activity against all bacteria. Second, the effect of extracts on free serum testosterone level in male mice in vivo, the alcoholic, and acetonitrilic extracts showed significant (P 0.05) increase in free serum testosterone level, and we found that the extracts contained compounds with less genotoxic effects in mice germ cells.