Author/Authors :
Salih, S Bin King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Kharal, M King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Qahtani, M King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Dahneem, L King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Nohair, S King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia
Abstract :
Acute oliguric renal failure (ARF) developed in a patient 2 days after she was started on intermittent anti-Brucella therapy including rifampicin. The clinical picture was compatible with acute allergic interstitial nephritis. Renal histology revealed mainly acute tubular necrosis with mild tubulo-intertitial mononuclear cellular infiltrate. Intermittent therapy, as in our patient, has been the major factor in the development of rifampicin induced ARF in cases reviewed in literature.
