• Title of article

    Acute Interstitial Nephritis induced by Intermittent use of Rifampicin in Patient with Brucellosis

  • Author/Authors

    Salih, S Bin King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Kharal, M King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Qahtani, M King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Dahneem, L King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia , Nohair, S King Abdulaziz Medical City - Division of Internal Medicine, Saudi Arabia

  • From page
    450
  • To page
    452
  • Abstract
    Acute oliguric renal failure (ARF) developed in a patient 2 days after she was started on intermittent anti-Brucella therapy including rifampicin. The clinical picture was compatible with acute allergic interstitial nephritis. Renal histology revealed mainly acute tubular necrosis with mild tubulo-intertitial mononuclear cellular infiltrate. Intermittent therapy, as in our patient, has been the major factor in the development of rifampicin induced ARF in cases reviewed in literature.
  • Journal title
    Saudi Journal of Kidney Diseases and Transplantation
  • Journal title
    Saudi Journal of Kidney Diseases and Transplantation
  • Record number

    2674239