Author/Authors :
Beiraghdar, Fatemeh baqiyatallah university of medical sciences - Nephrology and Urology Research Center, تهران, ايران , Maddani, Abbas tehran university of medical sciences tums - Pediatric Center - Nephrology Unit of Medical, تهران, ايران , Taheri, Saeed baqiyatallah university of medical sciences - Nephrology and Urology Research Center, تهران, ايران , Taheri, Saeed Dr Taheri Medical Research Group, ايران , Sharifi-Bonab, Mir Mohsen tabriz university of medical sciences - Neurology Department, تبريز, ايران , Esfahani, Taher tehran university of medical sciences tums - Medical Pediatric Center - Nephrology Unit, تهران, ايران , Panahi, Yunes baqiyatallah university of medical sciences - Nephrology and Urology Research Center, تهران, ايران , Panahi, Yunes Research Center for Chemical Injuries, ايران , Einollahi, Behzad baqiyatallah university of medical sciences - Nephrology and Urology Research Center, تهران, ايران
Abstract :
In this study, we aimed to analyze features and outcome of convulsion in pediatric lupus nephritis patients. We retrospectively reviewed data of 14 Iranian children with lupus nephritis who developed seizures and compared them with a group of the same number of well matched pediatric lupus nephritis patients. Higher serum creatinine levels and higher frequencies of anemia and lymphopenia were observed in the convulsion group. Multivariable logistic regression analysis revealed that the only risk factor for development of convulsion in pediatric lupus patients with nephritis was lymphopenia. Survival analysis showed that convulsion had no impact on patient and renal function outcomes in our pediatric lupus nephritis subjects. In conclusion, we found that lymphopenia is a predictive factor for convulsion occurrence in our patients and special attention to neurological status assessment may be needed in this situation.
Keywords :
Pediatric , Childhood , SLE , Lupus nephritis , Convulsion , Neurological manifestations
