Title of article :
Visceral leishmaniasis in a renal transplant recipient treated with allopurinol
Author/Authors :
Harzallah, Kais Military Hospital - Unity of Organ Transplantation, Tunisia , Belhadj, Raoudha Military Hospital - Unity of Organ Transplantation, Tunisia , Jemli, Boutheina Military Hospital - Department of Parasitology, Tunisia , Haloues, Mondher Military Hospital - Unity of Organ Transplantation, Tunis , Berraies, Naoufel Military Hospital - Department of Urolog, Tunisia , Gargouri, Saadia Military Hospital - Department of Parasitology, Tunisia , Hmida, Jalel Military Hospital - Coordinator of the Transplantation Program, Tunisia , Battikh, Riadh Military Hospital - Department of Internal Medicine - Unity of Hemodialysis, Tunisia , Manaa, Jamel Military Hospital - Unity of Organ Transplantation, Tunisia
From page :
105
To page :
108
Abstract :
Leishmaniasis is an infection caused by a protozoan parasite belonging to the genus Leishmania and transmitted by the Phlebotomus sandfly. We report a case of visceral leishmaniasis in a 49-year-old male renal transplant recipient, a resident of the western part of Tunisia, which is an endemic zone for the disease. Just before and after the transplantation, the patient resided in Tunis, which is non-endemic for leishmaniasis. Visceral leishmaniasis occurred eight years after renal transplantation, and the clinical picture was characterized by fever and pancytopenia. Leish­maniae were detected by bone marrow aspiration. Pentavalent antimonal was used for 28 days and was substituted by allopurinol (20 mg/kg per day). One year after the infection, the patient remains totally asymptomatic. Our report suggests that visceral leishmaniasis may complicate the clinical course of organ transplantation and can be fatal, particularly when untreated. Relapses may occur after completion of the apparently effective treatment. Allopurinol could be a solution to avoid these relapses.
Journal title :
Saudi Journal of Kidney Diseases and Transplantation
Journal title :
Saudi Journal of Kidney Diseases and Transplantation
Record number :
2675003
Link To Document :
بازگشت