Author/Authors :
Zaki, Ahmed Lokmanya Tilak Municipal General Hospital - Department of Pediatrics, India , Chavan, Vishal Lokmanya Tilak Municipal General Hospital - Department of Pediatrics, India , Nagotkar, Leena Lokmanya Tilak Municipal General Hospital - Department of Pediatrics, India , Shanbag, Preeti Lokmanya Tilak Municipal General Hospital - Department of Pediatrics, India
Abstract :
enal tubular acidosis is a disorder of renal acidification characterized by hyperchloremic metabolic acidosis and a normal anion gap. Type 1 RTA is a disorder of the distal nephron resulting in failure to lower urinary pH, due either to excessive back-diffusion of hydrogen ions from the lumen to the blood or to inadequate transport of hydrogen ions. It can be familial or due to secondary causes like Sjogren s syndrome, chronic active hepatitis and systemic lupus erythematosus.