Title of article :
Prevalence of anemia in predialysis chronic kidney disease patients.
Author/Authors :
Shaheen, Faissal A. M. Saudi Center for Organ Transplantation, Saudi Arabia , Souqiyyeh, Muhammad Ziad Saudi Center for Organ Transplantation, Saudi Arabia , Al-Attar, Besher Adib Saudi Center for Organ Transplantation, Saudi Arabia , Karkar, Ayman Dammam Medical Complex - Kanoo Kidney Centre, Saudi Arabia , Al Jazairi, Ayman Mohammad Hikmat Al Noor Specialist Hospital, Saudi Arabia , Badawi, Laila Siraj King Fahad Hospital, Saudi Arabia , Ballut, Omar Mahmoud King Fahad Hospital, Saudi Arabia , Hakami, Ali Hassan King Fahad Hospital, Saudi Arabia , Naguib, Mohammad King Fahad Hospital, Saudi Arabia , Al-homrany, Mohammed Attiah Asser Central Hospital, Saudi Arabia , Barhamein, Majdah Yasin King Fahad Specialist Hospital, Saudi Arabia , Ahmed, Adel Mansoor King Fahad Hospital, Saudi Arabia , Khardaji, Maher Mohammad Buraidah Central Hospital, Saudi Arabia , Said, Said Abduslam King Khaled Hospital, Saudi Arabia
From page :
456
To page :
463
Abstract :
To evaluate the prevalence of anemia in a large cohort that comprises patients in different stages of chronic kidney disease (CKD) in the kingdom of Saudi Arabia (KSA),we conducted a multi-center cross-sectional study of a cohort of CKD patients who have not started dialysis. The study patients were recruited from the nephrology clinics in 11 different medical centers distributed all over the regions of the KSA. For the estimated glomerular filtration rate (GFR),we used the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation. There were 250 study patients who fulfilled the criteria for the study. The patients were stratified according to their GFR as follows: stage 1: 19 patients,stage 2: 35 patients,stage 3: 67 patients,stage 4: 68 patients,and stage 5: 61 patients. The composite of proteinuria and abnormal imaging in stages 1 and 2 was satisfied in 100% of the cases. The prevalence of anemia was elevated for the hemoglobin levels below 12 g/dL (the level at which the evaluation of anemia in CKD should be initiated) in the different stages of CKD,that is,42%,33%,48%,71%,and 82% in the stages from 1 to 5,respectively. The prevalence was also elevated for the hemoglobin levels below 11 g/dL (the minimum hemoglobin level at which therapy should be initiated with erythropoietin),that is,21%,17%,31%,49%,and 72%,respectively for stages from 1 to 5. In conclusion,we found a large prevalence of anemia among the CKD population in Saudi Arabia,and the burden of patients who require treatment with erythropoietin is considerably large. However,the response to therapy will not require large doses according to the availability of long-acting erythropoiesis stimulating agents,which will render the therapy more convenient and less expensive.
Journal title :
Saudi Journal of Kidney Diseases and Transplantation
Journal title :
Saudi Journal of Kidney Diseases and Transplantation
Record number :
2675523
Link To Document :
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