Author/Authors :
Fatema, Kaniz Bangladesh University of Health Sciences (BUHS) - Department of Epidemiology, Bangladesh , Abedin, Zainal Endocrine and Metabolic Disorders (BIRDEM) Hospital - Bangladesh Institute of Research and Rehabilitation in Diabetes - Hemodialysis and Transplant Unit, Bangladesh , Mansur, Abul Endocrine and Metabolic Disorders (BIRDEM) Hospital - Bangladesh Institute of Research and Rehabilitation in Diabetes - Hemodialysis and Transplant Unit, Bangladesh , Rahman, Farzana Bangladesh University of Health Sciences (BUHS) - Department of Epidemiology, Bangladesh , Khatun, Taslima Bangladesh University of Health Sciences (BUHS) - Department of Community Nutrition, Bangladesh , Sumi, Nurunnahar Bangladesh University of Health Sciences (BUHS) - Department of Epidemiology, Bangladesh , Kobura, Khadizatul Bangladesh University of Health Sciences (BUHS) - Department of Epidemiology, Bangladesh , Akter, Selima Bangladesh University of Health Sciences (BUHS) - Department of Biochemistry and Cell Biology, Bangladesh , Ali, Liaquat Bangladesh University of Health Sciences (BUHS) - Department of Biochemistry and Cell Biology, Bangladesh
Abstract :
Chronic kidney disease (CKD) is now one of the major health problems all over the world and its early screening is vital to prevent the development of end-stage renal failure. This study was designed to evaluate the proportion of urban adults suffering from CKD as well as to have a preliminary idea about the determinants of this disorder. The screening program for CKD was arranged in a public place in Dhaka city,Bangladesh,and involved 634 adult participants ( 18 years of age) selected on first-come first-served basis. Socio-demographic,anthropometric,and clinical data were collected. Urinary protein was tested by the dipstick method,and serum glucose and creatinine were measured by an auto-analyzer. Estimated glomerular filtrate rate (eGFR) was calculated by using standard formula. CKD was diagnosed and classified according to the National Kidney Foundation (NKF) Kidney Disease Outcomes Quality Initiative (K/DOQI) guidelines. A total of 12.8% of the subjects were found to have CKD of whom 2.7% were in Stage 1,4.1% in Stage 2,and 6% were in Stage 3. The proportion was strongly influenced by age,with the highest prevalence (38.5%) found at 60 years and above. The CKD group showed higher body mass index,waist-hip ratio,and systolic blood pressure,compared with their non-CKD counterparts (P = 0.02). On multiple regression analysis (after adjustment of some confounding variables),age,random blood sugar,and education showed significant association with the development of CKD. A substantial number of urban adults in Dhaka were found to be unaware about the existence of CKD and large-scale prevention programs should be undertaken to reduce the classical risk factors of these disorders.
