Title of article :
Relapse of Sulfasalazine-Induced DRESS Syndrome Following the Administraton of Contrast Media: A Case Report
Author/Authors :
Mohebbi ، Niayesh Department of Clinical Pharmacy - Schoolof Pharmacy - Tehran University of Medical Sciences , Taghvaye-Masoumi ، Hamidreza Department of Clinical Pharmacy - Faculty of Pharmacy - Guilan University of Medical Sciences , Khosravi-Khezri ، Malihe Department of Clinical Pharmacy - Hasheminejad Kidney Center - Iran University of Medical Sciences , Talaschian ، Mona Department of Internal Medicine - Shariati Hospital - Tehran University of Medical Sciences
Abstract :
Sulfasalazine, a non-antibiotic sulfonamide, is associated with severe hypersensitivity reactions, including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. We report a case of sulfasalazine-induced DRESS syndrome that relapsed following the administration of visipaque® (iodixanol). Macular rashes, pruritus, and an acute exacerbation of dyspnea were immediately observed after the administration of contrast media. It seems that patients suffering from DRESS syndrome are sensitive to the administration of other new medications with a high possibility of hypersensitive reactions. It can be concluded that iodinated contrast media should be used cautiously in patients with DRESS syndrome.
Keywords :
Contrast media , Drug reaction with eosinophilia and systemic symptoms , Hypersensitivity reactions , Sulfasalazine
Journal title :
Case Reports in Clinical Practice
Journal title :
Case Reports in Clinical Practice
