Author/Authors :
Sepah, Yasir J. University of Nebraska - Medical Center, Ocular Imaging Research and Reading Center, Stanley M Truhlsen Eye Institute, USA , Akhtar, Abeer Johns Hopkins University - Retinal Imaging Research and Reading Center, Wilmer Eye Institute, USA , Akhtar, Abeer Harvard Medical School, USA , Sadiq, Mohammad Ali University of Nebraska - Medical Center, Ocular Imaging Research and Reading Center, Stanley M Truhlsen Eye Institute, USA , Hafeez, Yamama Johns Hopkins University - Retinal Imaging Research and Reading Center, Wilmer Eye Institute, USA , Nasir, Humzah Johns Hopkins University - Retinal Imaging Research and Reading Center, Wilmer Eye Institute, USA , Perez, Brian Johns Hopkins University - Retinal Imaging Research and Reading Center, Wilmer Eye Institute, USA , Mawji, Narissa Johns Hopkins University - Retinal Imaging Research and Reading Center, Wilmer Eye Institute, USA , Dean, Diana J. Creighton School of Medicine, Omaha , Ferraz, Daniel Johns Hopkins University - Retinal Imaging Research and Reading Center, Wilmer Eye Institute, USA , Nguyen, Quan Dong University of Nebraska - Medical Center, Ocular Imaging Research and Reading Center, Stanley M Truhlsen Eye Institute, USA
Abstract :
Fundus autofluorescence (FAF), a relatively new imaging modality, focuses on the fluorescent properties of pigments in the retina to generate images that help us view various disease processes from a different perspective. It aids us in the understanding of the pathophysiology of different retinal disorders. Recently, FAF imaging is being used commonly to help us in the diagnosis, prognosis as well as in determining the treatment response of various retinal disorders. It generates an image based on the distribution pattern of a fluorescent pigment called lipofuscin. Knowing the distribution pattern of lipofuscin in the normal retina is key to understanding an FAF image representing a retinal pathology. Like most other imaging modalities, FAF comes with its own limitations, taking steps to overcome these limitations will be of utmost importance in using this imaging modality to its fullest potential.
