Author/Authors :
Zarei, Reza tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Soleimani, Mohammad tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Moghimi, Sasan tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Kiarudi, Mohammad Yaser tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Jabbarvand, Mahmoud tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Eslami, Yadollah tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Abdollahi, Ali tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Panjtan Panah, Mohammad Reza tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Amini, Heydar tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران , Fakhraei, Ghasem tehran university of medical sciences tums - Farabi Eye Hospital - Eye Research Center, تهران, ايران
Abstract :
Purpose : To compare the ability of scanning laser polarimetry (GDx VCC), and optical coherence tomography (OCT) to discriminate eyes with primary open angle glaucoma (POAG) from normal eyes and to assess the relationship between their parametersMethods : Eighty-seven glaucomatous eyes of 87 patients and 25 normal eyes were enrolled. The mean age of patients and normal group were 54.96±18.34 and 50.02±20.15, respectively. All subjects underwent a full ophthalmic examination, automated perimetry, GDx VCC and OCT. Correlation coefficients between the parameters of OCT and GDx VCC were calculated. We calculated area under the receiver operating characteristic curve (AROC) for GDx VCC and OCT main parameters.Results : Statistically significant correlations were observed between GDx VCC and OCT parameters. Pearson coefficients ranged from 0.731 for inferior average to -0.858 for nerve fiber indicator (NFI)/average thickness of OCT. The greatest area under AROC parameter in OCT (inferior average 0.97) had a lower area than that in GDx VCC (NFI 0.99). There was a significant statistical correlation in all visual field (VF), GDx VCC, and OCT variables between two groups.Conclusion : Many parameters of GDx VCC were significantly correlated with those of the OCT. Inferior average and NFI had the greatest area under AROC parameter in OCT and GDx VCC, respectively. NFI had high sensitivity and specificity for the diagnosis of POAG
Keywords :
Primery Open Angle Glaucoma , GDx , Optical Coherence Tomography , Retinal Nerve Fiber Layer
