Author/Authors :
Al-Khuwaitir, Tarig S. Ministry of Health - Department of Medicine, Division of General Internal Medicine, Saudi Arabia , Al-Zuhair, Amin A. Ministry of Health - Department of Medicine, Division of General Internal Medicine, Saudi Arabia , Al-Ghamdi, Ali G. Ministry of Health - Department of Medicine, Division of General Internal Medicine, Saudi Arabia , Khan, Abdulaziz Ministry of Health - Department of Medicine, Division of General Internal Medicine, Saudi Arabia
Abstract :
Nalidixic acid-resistant Salmonella typhi (NARST) infections increase minimal inhibitory concentrations of fluoroquinolones, due to chromosomal mutations in the gene encoding DNA gyrase, and can lead to a delayed treatment response. This in turn alters the course of the disease allowing for a protracted period of illness and the occurrence of complications. In this case report, we present a patient from the Indian sub-continent, who was diagnosed with NARST complicated by sub-intestinal obstruction, her diagnosis, treatment, and subsequent recovery.
