Author/Authors :
Wibowo, Noroyono university of indonesia - Faculty of Medicine, Ciptomangunkusumo Hospital - Department of Obstetric and Gynecology, Indonesia , Mose, Johanes C. Padjajaran University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Karkata, Made K. Udayana University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Purwaka, Bangun T. Airlangga University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Kristanto, Herman Diponegoro University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Chalid, Maisuri T. Hasanuddin University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Yusrawati Andalas University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Sitepu, Makmur University of Sumatera Utara - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Kaeng, Juneke J. Sam Ratulangi University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Bernolian, Nuswil Sriwijaya University - Faculty of Medicine - Department of Obstetric and Gynecology, Indonesia , Pramusinto, Damar university of indonesia - Faculty of Medicine, Ciptomangunkusumo Hospital - Department of Obstetric and Gynecology, Indonesia , Irwinda, Rima university of indonesia - Faculty of Medicine, Ciptomangunkusumo Hospital - Department of Obstetric and Gynecology, Indonesia
Abstract :
Probiotics have been known for their use in medical field for quite a long time. Strong evidences are now available for the use of probiotics in clinical setting. One of the current issues on this topic is the use of probiotics in pregnancy. Recent studies showed that probiotics may be safe and beneficial for prenatal supplementation. In this review, we highlighted several proven use of probiotics supplementation in pregnant women. A few selected strains of probiotics showed promising outcome to prevent preterm labor and preeclampsia, and to reduce atopic eczema but not asthma and wheezing, in offspring of women who had prenatal probiotics supplementation. The mechanism of action responsible for this effect is closely related to the regulation of T cells, although the exact pathways are not defined yet.
Keywords :
preeclampsia , pregnancy , probiotics , prenatal supplementation , preterm labor
