Title of article
HYPOGLYCEMIC EFFECT OF ALOE VERA EXTRACT IN ALLOXAN-INDUCED DIABETIC ALBINO RATS
Author/Authors
JAFRI, SAGHIR A. The University of Lahore - Institute of Molecular Biology and Biotechnology, Pakistan , HASAN, SYED S. The University of Lahore - Institute of Molecular Biology and Biotechnology, Pakistan , NADEEM, AFTAB Shaukat Khanum Memorial Cancer Hospital and Research Centre - Department of Pathology, Pakistan , KALSOOM The University of Lahore - Institute of Molecular Biology and Biotechnology, Pakistan , IQBAL, JAVED Shaukat Khanum Memorial Cancer Hospital and Research Centre - Department of Pathology, Pakistan
From page
127
To page
130
Abstract
The present study was aimed to evaluate the antidiabetic activity of leaf extract of Aloe vera on forty adult male albino rats weighing 200-300 mg body weight (BW) which were divided into four groups (A, B, C and D), Group A served as control, Group B included normal rats treated with Aloe vera leaf extract (0.5 ml/100 gm BW), Group C and D were made diabetic by alloxan injection (65 mg/100 gm BW). Group C served as diabetic control while Group D was given Aloe vera leaf (AVL) extract at the same dose to Group B for 30 days. After 30 days the blood serum was analyzed for serum glucose level in all the four Groups. Twenty rats were randomly taken from these 40 rats for a follow up study and were not given AV extract. The serum glucose level was significantly (P . 0.05) decreased in AVL extract feeded rats in Group B and D indicating its hypoglycemic effect.
Keywords
aloe vera , diabetic , albino rats , alloxan
Journal title
Medical Journal of Islamic World Academy of Sciences
Journal title
Medical Journal of Islamic World Academy of Sciences
Record number
2682440
Link To Document