Title of article
Synthesis of 10H-Phenothiazines, their Sulfones and Ribofuranosides as Potential Chemotherapeutic Agents
Author/Authors
Dixit, Rahul University of Rajasthan - Department of Chemistry, India , Gautamb, Naveen , Gautama, D.C. University of Rajasthan - Department of Chemistry, India
Pages
9
From page
357
To page
365
Abstract
10H-phenothiazines are prepared by Smiles rearrangement. These prepared phenothiazines are used as base to prepare ribofuranosides by treatment with b-D-ribofuranosyl-1-acetate-2,3,5-tribenzoate. 10H-Phenothiazines on refluxing with hydrogen peroxide in glacial acetic acid gave 10H-phenothiazine-5,5-dioxides. Their antioxidant and antimicrobial activity have been carried out. The structure of the synthesized compounds have been established by spectroscopic data.
Keywords
Phenothiazines , Smiles rearrangement , Ribofuranosides , Antioxidant activity and antimicrobial activity
Journal title
Jordan Journal of Chemistry
Serial Year
2008
Journal title
Jordan Journal of Chemistry
Record number
2682918
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