Title of article :
The Effect of Curcumin on HDL Cholesterol Uptake Capacity in Obese Individuals: A Pilot Study
Author/Authors :
Saberi-Karimian ، Maryam Lung Diseases Research Center - Mashhad University of Medical Sciences , Nosrati ، Mina International UNESCO center for Health Related Basic Sciences and Human Nutrition - Mashhad University of Medical Sciences , Orooji ، Arezoo Department of Epidemiology and Biostatistics - Student Research Committee, Faculty of Health - Mashhad University of Medical Sciences , Kazemi ، Tooba Razi Clinical Research Development Unit (RCRDU) - Cardiovascular Diseases Research Center - Birjand University of Medical Sciences , Javandoost ، Ali International UNESCO center for Health Related Basic Sciences and Human Nutrition - Mashhad University of Medical Sciences , Mohammadi ، Akram International UNESCO center for Health Related Basic Sciences and Human Nutrition - Mashhad University of Medical Sciences , Ferns ، Gordon A. Division of Medical Education - Brighton Sussex Medical School , Aghasizadeh ، Malihe Department of Molecular Medicine - Cardiovascular Diseases Research Center, Faculty of Medicine, Student Research Committee - Birjand University of Medical Sciences , Ghayour-Mobarhan ، Majid International UNESCO center for Health Related Basic Sciences and Human Nutrition - Mashhad University of Medical Sciences
Abstract :
Introduction: Obesity is a common risk factor associated with cardiovascular disease (CVD) risk. Curcumin has been reported to exert beneficial effects on lipid metabolism, including HDL functionality. We have examined the effects of curcumin on HDL cholesterol uptake capacity in subjects with obesity. Materials and Methods: 30 obese individuals received curcumin and placebo 1 g per day for a period of 30 days. The subjects were crossed over to the alternative regimen after a 2-week washout period. A modified cholesterol uptake capacity (CUC) assay was used to determine serum HDL functionality. Results: The study groups had similar base line characteristics. We did not find significant effects (p 0.05) of curcumin on serum HDL CUC levels. Conclusion: Curcumin administration at a dose of 1 g per day for 30 days did not affect HDL CUC in subjects with obesity.
Keywords :
Curcuma Longa , Curcumin , Cholesterol Uptake Capacity , Metabolic Syndrome
Journal title :
Journal of Cardio- Thoracic Medicine
Journal title :
Journal of Cardio- Thoracic Medicine
