Title of article :
Long Non-coding RNAs Associated with Brain Disorders: A Literature Review
Author/Authors :
Abdolmaleki ، Arash Department of Engineering Sciences - Faculty of Advanced Technologies - University of Mohaghegh Ardabili , Ferdowsi ، Sevin Department of Biology - Faculty of Science - University of Mohaghegh Ardabili , Asadi ، Asadollah Department of Biology - Faculty of Science - University of Mohaghegh Ardabili , Panahi ، Yassin Pharmacology Toxicology Department - School of Pharmacy - Ardabil University of Medical Sciences
Abstract :
Context: Neurodegenerative diseases (NDs) are neurological disorders characterized by the degeneration of the central nervous system (CNS). Studies have examined interactions between long non-coding RNAs (lncRNAs) and functioning of the CNS in NDs. In this study, we summarized the role of different lncRNAs in most NDs. Methods: In this study, different papers published between years 2003 and 2020 were reviewed. Results: LncRNAs can play a significant role in the development of brain disorders. Conclusions: The dysregulation of lncRNAs has been shown to affect NDs such as Alzheimer s disease (AD) and Parkinson’s diseases (PD). In this review, we compiled recent findings related to the main lncRNAs associated with brain disorders.
Keywords :
Brain Disorders , Lncrna , Neurodegenerative Diseases , Nervous System
Journal title :
Gene Cell Tissue
Journal title :
Gene Cell Tissue
