GC/MS ANALYSES, ANTI-INFLAMMATORY AND ANTI-MICROBIAL ACTIVITIES OF THE VOLATILE CONSTITUENTS OF THREE CLEMATIS SPECIES GROWING IN SAUDI ARABIA

A comparative study of the volatile constituents of three Clematis species growing in Saudi Arabia namely Clematis hirsute Guillemin Perr, C. simensis Fresen and C. wightiana Wallich was carried out using GC/MS technique. Protoanemonin, eugenol and butylated hydroxyltoluene were the most abundant common constituents in the three species. Volatiles of Clematis hirsute and C. simensis showed closely similar MIC when tested against Gram-positive, Gram-negative bacteria and fungi. While those of C. wightiana were less active. Similarly, the anti-inflammatory activity of C. wightiana was less than that of the other two species