Author/Authors :
Çelik, Yahya Departments of Neurology - Medical Faculty of Trakya University, Edirne , Birgili, Özlem Department of Neurology - Edirne State Hospital, Edirne, Turkey , Yılmaz, Hakan Department of Neurology - Edirne State Hospital, Edirne, Turkey , Kiyat, Aslı Cerrahpaşa Medical Faculty - Department of Neurology - İstanbul University, İstanbul, Turkey , Saip, Sebahattin Cerrahpaşa Medical Faculty - Department of Neurology - İstanbul University, İstanbul, Turkey , Siva, Aksel Cerrahpaşa Medical Faculty - Department of Neurology - İstanbul University, İstanbul, Turkey , Güldiken, Baburhan Department of Neurology - School of Medicine - Trakya University, Edirne, Turkey , Özkan, Hülya Edirne Devlet Hastanesi Nöroloji Kliniği, Edirne , Kuşçu, Dilek Department of Neurology - Bakırköy State Hospital, İstanbul, Turkey , Sütlas, Nevin Department of Neurology - Bakırköy State Hospital, İstanbul, Turkey , Ağaoğlu, Jale Department of Neurology - Okmeyadanı State Hospital, İstanbul, Turkey , Utku, Ufuk Trakya Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, Edirne
Abstract :
Objective: The prevalence and incidence of multiple sclerosis may vary according to the influence of the altitude of a geographical area as well as the genetic and environmental factors. This study ained to determine the incidence and prevalence of multiple sclerosis in Edirne population. Material and Methods: Patients with a definite diagnosis of MS according to McDonald’s criteria, admitted to one of the three MS clinics in Edirne, were included in this two-stage study. Also the records of hospitals in Ýstanbul serving patients from Edirne, have been evaluated. Results: The prevalence rate of confirmed MS patients was 33.9/100000 (95% CI: 32-36) in 2003. The mean annual incidence was 3.48/100000 (95% CI: 2.90-4.00). Mean age of the patients was 36.5±9.6 years. Mean age at onset was 29.2±8.5 years. Mean duration of disease was 6.9±5.2 years. Overall, 69.2% had a relapsing-remitting course, 20.5% had a primary progressive course and 10.3% had a secondary progressive course. Mean Expanded Dis- ability Status Scale score was 3.04±2.18. The prevalence and annual incidence after one year was 36.5 per 100000 (95% CI: 33.2-38.6) and 2.60 per 100000 (95% CI: 2.1-3.8), respectively. Conclusion: This is the first city-based MS prevalence study performed in Turkey. The MS prevalence in Edirne is similar to that of Greece and Bulgaria but lower than that of European countries.
Keywords :
Multiple Sclerosis , prevalance , incidence , epidemiology , Turkey
