Author/Authors :
Kılbaş, Zafer Gülhane Askeri Tıp Akademisi - Genel Cerrahi Anabilim Dalı, Ankara, Türkiye , Yiğit, Taner Gülhane Askeri Tıp Akademisi - Genel Cerrahi Anabilim Dalı, Ankara, Türkiye , Öner, Köksal Gülhane Askeri Tıp Akademisi - Genel Cerrahi Anabilim Dalı, Ankara, Türkiye , Kozak, Orhan Gülhane Askeri Tıp Akademisi - Genel Cerrahi Anabilim Dalı, Ankara, Türkiye , Ilgan, Seyfettin Gülhane Askeri Tıp Akademisi - Nükleer Tıp Anabilim Dalı, Ankara, Türkiye , Ilgan, Seyfettin Gülhane Askeri Tıp Akademisi - Nükleer Tıp Anabilim Dalı, Ankara, Türkiye , Arslan, Nuri Gülhane Askeri Tıp Akademisi - Nükleer Tıp Anabilim Dalı, Ankara, Türkiye , Menteş, Öner Departments of General Surgery - Gülhane Military Medical School, Ankara , Tufan, Turgut Departments of Anesthesiology - Gülhane Military Medical School, Ankara
Abstract :
Objective: Whole-body fluorodeoxyglucose-positron emission tomogra- phy (FDG-PET) has proved effective in the diagnosis of recurrent colorec- tal cancer (CRC) and in the monitoring of cancer therapy. However there have been limited studies considering the effect of FDG-PET in the initial evaluation of CRC. We analysed how FDG-PET affects the management of patients with CRC preoperatively. Material and Methods: A prospective study of 26 consecutive patients with known or suspected CRC was undertaken. The patients were evalu- ated by computed tomography (CT) and FDG-PET. FDG-PET results were compared with those of CT and correlated with histopathologic fi ndings or with clinical course. Results: FDG-PET had a sensitivity of 96% and positive predictive value of 100% for the diagnosis of primary cancer, while CT had values of 68% and 95%, respectively. FDG-PET was superior to CT in detecting additional metastatic disease with a sensitivity of 89%, while CT had 33%. FDG-PET resulted in altered management for 8 patients of whom three avoided inappropriate surgery. Conclusion: It is concluded that FDG-PET is highly sensitive for the di- agnosis and staging of patients with CRC. Its use in conjunction with CT results in a more accurate selection of patients for surgical treatment with curative intent.
Keywords :
Colorectal cancer , FDG , PET , patient management
