Author/Authors :
Sağıroğlu, Gönül Sağlık Bakanlığı Süreyyapaşa Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi - Anesteziyoloji ve Reanimasyon Kliniği, İstanbul, Turkey
Abstract :
Objective: In our study, we aimed to compare epidural morphine and fentanyl analgesia and the side effects in post-thoracotomy pain manage- ment. Material and Methods: Forty patients, planned for elective thoracoto- my were included. Bupivacain- morphine was administered through an epidural catheter to the patients in Group-M while bupivacain-fentanyl was given in Group-F. Pain assessment was carried out with the Visual Analogue Scale (VAS) and VAS-I and VAS-II were assessed in 0, 4, 16 and 24th hour in the postoperative unit. Adverse effects were recorded after the 24th hour. Statistical analyses were performed by using Two-sample independent-t test, Mann Whitney-U test, Wilcoxon-signed ranks test and Pearson chi-squared tests. Results: Although, the VAS-I and VAS-II scores were lower in Group-M than Group-F, the difference was not significant statistically (p 0.05). When other hours were compared with initial states, beginning from the 4th hour, in both groups there was a statistically significant drop in VAS-I and VAS-II scores at all times (p 0.001). Comparing the complications between the groups, in Group-M nausea-vomiting (p 0.015) and brady- cardia (p 0.012) were found significantly more frequently than in Group-F. Conclusion: We concluded that, in pain management after thoracic sur- gery, either morphine or fentanyl may be chosen in thoracal epidural an- algesia but, especially in the early postoperative hours, close follow-up is necessary due to the risk of bradycardia development.