Evaluation of Effects of Enrofloxacin on Some Haematological Parameters in Broilers

In the present study, effects of enrofloxacin overdose on some haematological parameters of broiler chickens were investigated. A total of 50, Ross-308 one-day-old male broiler chickens were used. Broilers (10 days old) were divided into four groups: Animals in Group 1 (kept as control) and Group 2, 3 and 4 were administered 10, 100 and 200mg/kg body weight enrofloxacin for 30 consecutive days, respectively. Samples of blood were then collected to determine the haemato-logical values. Haematological parameters were determined manually. Results revealed that the RBC decreased in Group 3 and 4; the Hb increased in Group 2 and decreased in Group 3 and 4; the MCV levels were higher in Group 3 and 4; the MCH increased in Group 2, 3 and decreased in Group 4; the MCHC decreased in Group 3 and 4. There were declines in the WBC in Group 3 and 4. The results suggest that the oral administration of enrofloxacin at approximately 10- and 20-fold of the proposed dosage of 10 mg /kg for up to 30 days altered some haematological parameters in broiler chickens. Additionally, it was shown that the resultant anaemia and leucopoenia occurred in broilers.