Synthesis and Characterization of N-((6- substituted - Benzothiazol -2-Y) succinamic acid, 3-(6- substituted -benzothiazoI-2-Yl) - Carbamoyl Propionyl Chloride and study of their Biological effects

Twelve N-(6-substituted -benzoihiazol-2- y! ) - Succinamic acids and 3-(6- substitutcd -bcnzothiazo1-2-yi)-carbamoyl propionyl chloride were synthesized in good yields from reaction of 3- bcnzolhiazoI-2-yi)-carbamoyl acrylic acid with thionyl chloride and (he yield reacted with bromine solution . The resulting compounds arcidentified by their mps, Elemental Analysis,IR.,UV.and HNMR.spectra. Their structural formul were on firmed. The biological activity of these compounds studie with a group of bacteria isolate and were compared with anti-biolics.The compounds had shown varying activityes depending on their cocentrations and the type of the substituting group