Total Serum Sialic Acid Among Enteric Fever Patients

In this study, serum total sailie acid concentration were tested as a serological marker of diseases activity, to evaluate the rules of the test in the diagnosis of enteric fever, (TSA) was measured in the serum of (50) patients with typhi fever, (50) patients with paratyphi fever, (50) patients with disease other then enteric fever as pathological control, (50) normal healthy persons as normal healthy control. This study revealed that TSA increases significantly in typhoid patients and pathological control (88 mg/dl) (99 nig/dl) respectively as compared in normal healthy, hut there is no significant differences between thyphoid patients as compare to pathological control (P 0.05), and there is no difference between typhi fever and paratyphi fever (P 0.05)J lowever the test has low specificity and sensiti ity leading to sever limitation of the test, which seems of no value as biochemical marker in typhoid patients, so that we can say that serum (TSA) is a general marker for fever rather than a specific marker