Author/Authors :
Sagheb, MM shiraz university of medical sciences - Section of Nephrology, Department of Medicine, شيراز, ايران , Sharifian, M shiraz university of medical sciences, شيراز, ايران , Moini, M shiraz university of medical sciences, شيراز, ايران , Ghotbi, Sh fasa university of medical sciences - Department of Obstetrics and Gynecology, ايران
Abstract :
Henoch_Schoenlein Vasculitis following drug administration is not so common. Here, a case of Henoch_Schoenlein Vasculitis caused by Ranitidine and Naproxen is described which presented with fever, vomiting bloody diarrhea, palpable purpura and azotemia. Histology of the skin showed leukocytoclastic vasculitis of superficial vessels and direct immunofluorescence revealed immunoglobulin A (IgA) in superficial dermal vessels and so confirmed the diagnosis. The patient was traeted with Ranitidine discontinuation and Prednisone administration. A short review of literature is also made.