Title of article :
Frequency of HLA Antigens in a Sample of Iraqi Brucellosis Patients
Author/Authors :
Ad hiah, Ali H. University of Baghdad - College of Science - Tropical-Biological Research Unit, Iraq , Al-Rikaby, Aaiad H. A. University of Baghdad - College of Education Ibin Al-Haitham - Department of Biology, Iraq , Jasim, Ammna N. University of Baghdad - College of Science for Women - Department of Biology, Iraq
Abstract :
Fifty one patients with serologically confirmed brucellosis and 70 healthy controls were phenotyped for HLA-A, -B, -DR and -DQ antigens by using standard microlympho-cytotoxicity method, and lymphocytes defined by their CD markers (CD3, CD4, CD8 and CD19). The results revealed a significant (Pc = 0.001) increased frequency of HLA-DR8 (41.18 vs. 10.0%) in the patients . A significant increased percentage of CD8+ lymphocytes was also increased in the patients (25.15 vs. 22.0%; P = 0.006), while CD3+ lymphocytes were significantly decreased (75.1 vs. 79.4%; P = 0.02).
Keywords :
Brucellosis , HLA , CD markers
Journal title :
Baghdad Science Journal
Journal title :
Baghdad Science Journal
