Title of article :
Spectrophotometric method for the determination of Captopril in pharmaceutical formulations
Author/Authors :
Mohammed, Dawood H. Mosul University - Education College for Girls - Chemistry Department, Iraq , Shehab, Intesar A. Mosul University - Education College for Girls - Chemistry Department, Iraq , Ahmed, Hend Mosul University - Education College for Girls - Chemistry Department, Iraq
Abstract :
A simple, rapid and sensitive spectrophotometric method has been developed for the determination of captopril in aqueous solution. The method is based on reaction of captopril with 2,3-dichloro 1,4- naphthoquinon(Dichlone) in neutral medium to form a stable yellow colored product which shows maximum absorption at 347 nm with molar absorptivity of 5.6 ×10^3 L.mole^-1. cm^-1. The proposed method is applied successfully for determination of captopril in commercial pharmaceutical tablets.
Keywords :
Spectrophotometry , Captopril , Dichlone , 2,3 , dichloro 1,4 , naphthoquinon.
Journal title :
Baghdad Science Journal
Journal title :
Baghdad Science Journal
