Author/Authors :
Mauf, Ruwa M. University of Mosul - College of education for Girels - Department of Chemistry, Iraq , Sultan, Asmaa H. University of Mosul - College of Science - Department of Chemistry, Iraq , Farag, AmeeraM. University of Mosul - College of Science - Department of Chemistry, Iraq
Abstract :
Chloroacetamide derivatives (2a-g) have been prepared through reaction of chloroacetyl chloride(1) (which prepared by the reaction of chloroacetic acid with thionyl chloride) with primary aromatic amines and sulfa compounds to afford compounds (2a-g) which then reacted with p-hydroxy benzaldehyde via Williamson reaction to obtaine the new compounds 2-(4-formyl phenoxy)-N-aryl acetamide (3a-g). Finally , compounds (3a-g) will be use as a good synthon to prepare the Schiff bases represented by compounds 2-(4-aryliminophenoxy)-N-arylacetamide (4a-g). through , reaction with some primary aromatic amine. All the prepared compounds were investigated by the available physical and spectroscopic methods
