Author/Authors :
Al-Futaisi, Amna Sultan Qaboos University Hospital - Department of Child Health, Oman , Al-Azri, Faisal Sultan Qaboos University Hospital - Department of Radiology Molecular Imaging, Oman , Abdelmogheth, Anas A. Sultan Qaboos University Hospital - Department of Child Health, Oman , Al-Murshedi, Fathiya Sultan Qaboos University Hospital - Departments of Genetics, Oman , Koul, Roshan Sultan Qaboos University Hospital - Department of Child Health, Oman
Abstract :
Acute disseminated encephalomyelitis (ADEM) is a monophasic, inflammatory central nervous system (CNS) demyelinating disease that usually affects children more than adults.1 The International Pediatric Multiple Sclerosis (MS) Study Group defines ADEM as the “first clinical event with a presumed inflammatory or demyelinating cause, with acute or sub acute onset that affects multifocal areas of the CNS”.2 A polysymptomatic presentation, along with evidence of encephalopathy, such as behavioural changes or lethargy, must be present for the diagnosis.
