Author/Authors :
Mobarak, Sara Clinical Research Development Unit - Taleghani Educational Hospital - Abadan University of Medical Sciences, Abadan , Mohammadi, Asma Clinical Research Development Unit - Valiasr Educational Hospital - Abadan University of Medical Sciences, Abadan , Zahedi, Atefeh Department of Public Health - Asadabad School of Medical Sciences, Asadabad , Jelvay, Saeed Clinical Research Development Unit - Valiasr Educational Hospital - Abadan University of Medical Sciences, Abadan , Maghsoudi, Fatemeh Department of Public Health - School of Health - Abadan University of Medical Sciences, Abadan , Assareh Zadegan Dezfuli, Mohammad Hosein Abadan University of Medical Sciences, Abadan , Balizadeh Karami, Ali Reza Abadan University of Medical Sciences, Abadan , Radmanesh, Esmat Abadan University of Medical Sciences, Abadan
Abstract :
SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) was first known in Wuhan,
China, in December 2019. The aim of this study was to evaluate the level of common hepatic, renal, and
cardiac diagnostic markers in hospitals in patients with severe COVID 19. In this study, 259 patients with
symptoms of severe COVID-19 and a positive RT-PCR assay of nasopharyngeal samples were enrolled.
Inclusion criteria are positive for COVID-19 patients at the diagnosis of an infectious disease physician.
Diagnostic markers of liver, kidney, and heart were evaluated by age and gender. In this study, 48.3% of
patients severe with COVID-19 were male, and 51.7% were female. The mean of markers such as LDH,
Direct Bilirubin, SGOT, SGPT, D-dimer was higher than normal, which was observed in men more than
women. The mean of CK-MB also was higher than normal, which was observed in women more than men.
The highest mean of markers was seen in the older ages. The mean of BUN was observed in the age range of
55-64 years and above 65 years above normal. But the mean of CPK, creatinine, potassium and alkaline
phosphatase were normal. The results of the present study showed an increase in the level of some of the
most important diagnostic markers of hepatic, renal, and cardiac in patients with COVID 19. This increase
was greater in some markers, including SGOT, SGPT, Direct bilirubin, LDH, D-dimer, in men than in
women, and more in older patientsSARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) was first known in Wuhan,
China, in December 2019. The aim of this study was to evaluate the level of common hepatic, renal, and
cardiac diagnostic markers in hospitals in patients with severe COVID 19. In this study, 259 patients with
symptoms of severe COVID-19 and a positive RT-PCR assay of nasopharyngeal samples were enrolled.
Inclusion criteria are positive for COVID-19 patients at the diagnosis of an infectious disease physician.
Diagnostic markers of liver, kidney, and heart were evaluated by age and gender. In this study, 48.3% of
patients severe with COVID-19 were male, and 51.7% were female. The mean of markers such as LDH,
Direct Bilirubin, SGOT, SGPT, D-dimer was higher than normal, which was observed in men more than
women. The mean of CK-MB also was higher than normal, which was observed in women more than men.
The highest mean of markers was seen in the older ages. The mean of BUN was observed in the age range of
55-64 years and above 65 years above normal. But the mean of CPK, creatinine, potassium and alkaline
phosphatase were normal. The results of the present study showed an increase in the level of some of the
most important diagnostic markers of hepatic, renal, and cardiac in patients with COVID 19. This increase
was greater in some markers, including SGOT, SGPT, Direct bilirubin, LDH, D-dimer, in men than in
women, and more in older patients
