Author/Authors :
Najafizadeh, Katayoun shahid beheshti university of medical sciences - Lung Transplantation Research Center - Department of Pulmonary Medicine, تهران, ايران , Shiehmorteza, Masoud shahid beheshti university of medical sciences - Department of Pulmonary Medicine, تهران, ايران , Ghorbani, Fariba shahid beheshti university of medical sciences - Department of Pulmonary Medicine, تهران, ايران , Jamali, Masoud shahid beheshti university of medical sciences - Department of Pulmonary Medicine, تهران, ايران
Abstract :
Post-transplant diabetes mellitus (PTDM), developing in almost one quarter of renal transplant patients within three years after the procedure, contributes to post-transplant morbidity and mortality by increasing the risk of infection and cardiovascular events. PTDM is considered a variant of diabetes mellitus (DM) type II and results in similar microvascular and macrovascular diabetic complications seen in non-transplant patients. In this article, we present a case of single lung transplant patient who developed PTDM with a severe DKA as the first manifestation of the disease. PTDM resolved rapidly after discontinuing tacrolimus.
Keywords :
Diabetic ketoacidosis , Immunosuppressive agents , Adverse effects , Tacrolimus , Treatment outcome , Lung transplantation