E-page Original Images: Coronary aneurysm and factor V Leiden mutation: A coincidence or an association?

A 23-year-old male referred to our tertiary cardiology center because of chest pain, 3 ventricular fibrillation episodes in last 12 hours and troponin T elevation (1.2 μg/l). His medical history revealed recurrent deep venous thrombosis attacks on his left leg and one pulmonary embolism attack. He was a homozygous mutant on factor V Leiden mutation analysis. The patient had no clinical or laboratory evidence of autoimmune or infectious illnesses. Early coronary angiography showed an 80% diameter stenosis and an aneurysm with a maximal diameter of 12 mm at the same site of mid-circumflex artery.